This study will compare how well a combination of borage and echium oils will reduce inflammation compared to fish oils and placebo oil in subjects that are diabetic or have metabolic syndrome.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
80
Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, United States
Fasting Insulin
Time frame: baseline
Fasting Insulin
Fasting insulin data at 4 and 8 weeks was averaged.
Time frame: 4 weeks and 8 weeks combined
hsCRP
Changes in high sensitive C-reactive protein (hsCRP) were assessed.
Time frame: baseline
hsCRP
Changes in high sensitive C-reactive protein (hsCRP) were assessed and data at 4 and 8 weeks was averaged..
Time frame: 4 weeks and 8 weeks combined
Leptin
Time frame: baseline
Leptin
Data at 4 and 8 weeks was averaged.
Time frame: 4 weeks and 8 weeks combined
Serum Fatty Acids
Time frame: baseline
Serum Fatty Acids
Data at 4 and 8 weeks was averaged.
Time frame: 4 weeks and 8 weeks combined
Pro and Anti-inflammatory Cytokines
Time frame: baseline
Pro and Anti-inflammatory Cytokines
Time frame: 4 weeks and 8 weeks combined
Fasting Glucose
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Time frame: baseline
Fasting Glucose
Data at 4 and 8 weeks was averaged.
Time frame: 4 weeks and 8 weeks combined
Hemoglobin Levels
Time frame: baseline
Hemoglobin Levels
Data at 4 and 8 weeks was averaged.
Time frame: 4 weeks and 8 weeks combined
Adipose Derived Cytokines
Time frame: 4 weeks
PBMC Gene Expression
Time frame: baseline
PBMC Gene Expression
Time frame: 4 weeks
SNPs in DNA of Selected Genes
Time frame: baseline
SNPs in DNA of Selected Genes
Time frame: 4 weeks
PBMC Leukotriene Stimulation
Time frame: baseline
PBMC Leukotriene Stimulation
Time frame: 4 weeks