A Comparison Between Signature Total Knee Arthroplasty (TKA) to Conventional TKA and Computer Assisted TKA

Inclusion Criteria: * Patient is of legal age and skeletally mature * Patient requires primary total knee arthroplasty due to non- inflammatory degenerative joint disease (e.g. osteoarthritis, traumatic arthritis, a vascular necrosis, dysplasia/DDH) or inflammatory joint disease (e.g., Rheumatoid arthritis). * Patient has met an acceptable preoperative medical clearance and is free from or treated for cardiac, pulmonary, haematological, etc., conditions that would pose excessive operative risk * The patient will be available for follow up throughout the duration of the study. Exclusion Criteria: * Patient is unable to have an MRI scan due to the following conditions: * Cardiac pacemaker * Surgical clips in head (aneurysm clips) * Some artificial heart valves * Electronic inner ear implants * Metal fragments in eyes * Electronic stimulators * Implanted pumps * Patient has active infection or sepsis (treated or untreated) * Patient has any vascular insufficiency, muscular atrophy, or neuromuscular disease severe enough to compromise implant stability or postoperative recovery. * Patient is female of child-bearing age and not taking contraceptive precautions. * Patient has inadequate bone stock to support the device (e.g. severe osteopenia, family history of severe osteoporosis or osteopenia). * Patient has known moderate to severe renal insufficiency. * Patient has a known or suspected metal sensitivity. * Patient is immunosuppressed or receiving high doses of corticosteroids. * Patient has an emotional or neurological condition that would pre-empt their ability or willingness to participate in the study including mental illness, mental retardation, or drug, alcohol abuse. * Patient has BMI \>40.