The purpose of this study is to determine the safety and efficacy of a short course of radiotherapy (40 Gy / 5 fractions / 29 days) for the treatment of low- and intermediate-risk prostate cancer.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
40 Gy / 5 fractions / 29 days
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Incidence of grade 3+ rectal toxicity
Common Terminology Criteria for Adverse Events (CTCAE) v3.0
Time frame: Acute period (<3 months)
Incidence of grade 3+ urinary toxicity
Common Terminology Criteria for Adverse Events (CTCAE) v3.0
Time frame: Acute (<3 months) and Late (>6 months)
Quality of Life
Expanded Prostate Cancer Index Composite (EPIC)
Time frame: 5 years
Biochemical (ie. prostate specific antigen) disease free survival
Time frame: 5 year
Incidence of grade 3+ rectal toxicity
Common Terminology Criteria for Adverse Events (CTCAE) v3.0
Time frame: Late (>6 months)
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