Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia

Inclusion Criteria: * Patients with hyperlipoproteinemia Type I or Type V willing and medically able to discontinue their lipid lowering medication (if prescribed). * Non breast feeding women. * Women of child bearing potential practicing appropriate contraception with a negative pregnancy test before dosing. Exclusion Criteria: Patients with: * uncontrolled type 1 or type 2 diabetes mellitus, * active pancreatitis (the month prior to study start), * history of drug or alcohol abuse within the 12 months prior to dosing, * or any surgical or medical condition, acute or unstable chronic disease which may, based on the investigator's opinion, jeopardize the patient in case of participation in the study. Other protocol-defined inclusion/exclusion criteria may apply