Single Oral Dose of 60 mg [14C]AZD9668 in Healthy Male Volunteers

AstraZeneca4 enrolled

Overview

The purpose of the study is to characterise the absorption, distribution, metabolism and excretion (ADME) of a single oral dose of \[14C\]AZD9668.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Healthy

Interventions

[C14]AZD9668DRUG

Oral Solution 60 mg Single Dose

Eligibility

Sex: MALEMin age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Provision of signed, written and dated informed consent prior to any study specific procedure * Have a body mass index (BMI) between 18 and 30 kg/m2 and weigh at least 50 kg Exclusion Criteria: * Exposed to radiation levels above background of \>5 mSv in the last year, \>10 mSv over the last 5 years or a cumulative total of \>1 mSv per year of life * History or presence of any clinically significant disease or disorder in the opinion of the investigator * Any clinically relevant abnormal findings in physical examination, clinical chemistry, haematology, urinalysis, vital signs or ECG at baseline in the opinion of the investigator

Locations (1)

Research Site

London, United Kingdom