Vascular inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis.Resistin was shown to induce vascular endothelial dysfunction and vascular smooth muscle cell proliferation. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for identifying and quantifying vascular inflammation within atherosclerotic plaques.Therefore, the purpose of the study is to demonstrate the correlation between circulating resistin and vascular inflammation detected by 18FDG-PET in obese persons.
Study Type
OBSERVATIONAL
Enrollment
120
This is not intervention study. The purpose of the study is to examine the relationship between various adipokine levels and PET imaging at the cross section setting
Hae Yoon Choi
Seoul, South Korea
Vascular inflammation in carotid arterial wall represented as the target-to-background ratio (TBR) using FDG-PET
Time frame: 12 weeks
Circulating serum adiponectin levels
Time frame: 12 weeks
carotid intima-media thickness levels measured using ultrasonography
Time frame: 12 weeks
Circulating serum resistin levels
Time frame: 12 weeks
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