A Study to Evaluate the Effect on 24-hour, Intragastric pH of RAB ER 50-mg Capsules Compared With Esomeprazole (Nexium) 40 mg Capsules and Rabeprazole (Aciphex) 20-mg Tablets

Key inclusion: * Healthy male and female subjects, including women of child-bearing potential, aged 18 to 55 years, inclusive * Subjects who are able to tolerate the insertion and placement of a pH probe on 2 occasions per study period (Day -1 and Day 5) Key Exclusion: * Subjects who are H. pylori-positive * Subjects who have a history of any gastrointestinal disorder or surgery likely to influence drug absorption (e.g., history of gastric resection) * Known hypersensitivity to rabeprazole, esomeprazole, or related compounds or any ingredient in the formulations * Other standard clinical pharmacology exclusion criteria for healthy volunteers