Sodium Management in Acute and Chronic Heart Failure

Ospedale G. F. Ingrassia

Overview

The study was aimed to verify the effects of Hypertonic saline solution (HSS) and a moderate sodium (Na) restriction plus high furosemide dose in the short term (hospitalization time) and a moderate Na restriction in the long term on readmissions and mortality in patients in III NYHA class.

Study Type

OBSERVATIONAL

Conditions

Heart Failure

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Decompensated HF due to ischemic or nonischemic cardiomyopathy, * \>18 years of age, * HF according to Framingham criteria * NYHA functional class III * EF \<40%, * Serum creatinine \<2,5 mg/dL * BUN \<60 mg/dL, Exclusion criteria: * NYHA class \> III or \< III, * Cerebral vascular disease, * Dementia, * Cancer, * Uncompensated diabetes, * Severe hepatic disease * Patients requiring pacemaker * Previous RCT implantation * Alcoholic habit

Locations (1)

GF Ingrassia Hospital

Palermo, Italy

Outcomes

Primary Outcomes

readmission for HF worsening

Secondary Outcomes

mortality

Data from ClinicalTrials.gov

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