Soluble Dietary Fibres in the Prevention of Type 2 Diabetes Mellitus

Maastricht University Medical Center60 enrolled

Overview

Controlling the glycemic impact of foodstuffs (by reducing the glycemic load of the diet by using soluble dietary fibres) may reduce the glycemic or insulinemic response. This may in turn result in a reduced inhibition of postprandial fat oxidation rate and a lower plasma triacylglycerol concentration A higher postprandial fat oxidation may result in less lipid accumulation in non-adipose tissue thereby improving insulin sensitivity and the metabolic profile in the longer term.

Study Type

INTERVENTIONAL

Enrollment

Conditions

Type 2 Diabetes Mellitus Obesity

Interventions

Polydextrose and soluble gluco fibreOTHER

Polydextrose and soluble gluco fibre

Eligibility

Sex: ALLMin age: 30 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Overweight men and women Exclusion Criteria: * regular smokers, athletes, diabetes mellitus

Locations (1)

Maastricht University

Maastricht, Netherlands

Outcomes

Primary Outcomes

fat oxidation

Secondary Outcomes

24h glucose pattern

Data from ClinicalTrials.gov

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