Creatine Supplementation and Bone Mass

University of Sao Paulo60 enrolled

Overview

Resistance training as well as creatine supplementation may increase bone mass. Therefore, the investigators speculate that resistance training combined with creatine supplementation would promote additive benefits on bone mass in elderly women with osteopenia and osteoporosis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Osteopenia Osteoporosis

Interventions

creatine supplementationDIETARY_SUPPLEMENT

20g/d for 7 days followed by 5g/d for 23 weeks

exercise trainingOTHER

resistance training twice a week for 24 weeks

placebo (dextrose)OTHER

20g/d for 7 days followed by 5g/d for 23 weeks

Eligibility

Sex: FEMALEMin age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * osteopenia and osteoporosis * women older than 60 years old Exclusion Criteria: * cardiovascular diseases or muscular disturbances precluding exercise training * drugs affecting bone metabolism

Locations (1)

School of Medicine - Division of Rheumatology

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

bone mineral density

Time frame: six months

Secondary Outcomes

cognition

Time frame: six months

physical capacity

including muscle strength, balance and muscle function

Time frame: six months

Data from ClinicalTrials.gov

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