How best to manage preeclampsia remote from term is controversial because of conflicting maternal and neonatal risks. Gestational age is the most important determinant of neonatal outcome. There are two basic approaches when delivery is not clear indicated by assessment of maternal and fetal well-being. The interventionist care when the delivery is planned within 48 hours and the expectant care which refers to pregnancy prolongation during which time women and fetuses are carefully monitored for indications for delivery. The purpose of this study is to evaluate maternal and perinatal outcomes with expectant vs interventionist or aggressive management of severe preeclampsia at 28 to 33 weeks of gestation.
Severa Preeclampsia between 28 and 33 weeks of gestation Women and fetus with stable condition All women receive complete dosis of steroids
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
264
Termination of pregnancy (delivery)after completed corticosteroids
Hospital Terodoro Maldonado, del IESS
Gauyas, Ecuador
Hospital Carlos Andrade Marin
Quito, Ecuador
Hospital de Gineco-Obstetricia del seguro social
Guatemala City, Guatemala
Hospital de Ginecologia del Instituto Materno Infantil
Toluca, Mexico
Complejo Hospitalario Caja de Seguro Social
Panama City, Provincia de Panamá, Panama
Hospital Santo Tomás
Panama City, Panama
Hospital Nacional Madre Niño, Lima Perú
Lima, Peru
Hospital Nuestra Señora de Chiquinquira
Maracaibo, Maracaibo, Venezuela
Perinatal death
Number of perinatal in each group (interventionist or expectant management)
Time frame: After begining the randomization until 4 weeks after delivery.
Perinatal complications and maternal complications
Time frame: Maternal and perinatal complication after begining the randomization until 4 weeks after delivery.
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