Short Term Feeding for Asian Patients With Liver Cirrhosis

University of Malaya52 enrolled

Overview

The benefits of short-term naso-gastric feeding in patients with advanced cirrhosis remain uncertain. This was a randomised study comparing naso-gastric feeding and oral feeding in Asian patients with cirrhosis who were admitted to hospital for decompensation.

Consecutive patients with decompensated cirrhosis who fitted the inclusion criteria, will be randomised to either naso-gastric or oral feeding. Total feeding will be for 2 weeks only. Following intervention specific nutritional and liver-related parameters will be measured during the 2 weeks and up to 6 weeks later. Comparison between both groups will then be made.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

CIRRHOSIS

Interventions

Osmolite and B.C.A.A.DIETARY_SUPPLEMENT

Feeding inserted into enteral tubes

Normal oral intake & supplementation if necessaryDIETARY_SUPPLEMENT

Enteral nutrition

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with decompensated cirrhosis of any etiology. Exclusion Criteria: * Advanced hepatic encephalopathy, * Variceal bleeding, * Hepatocellular carcinoma.

Locations (1)

University of Malaya Medical Centre

Kuala Lumpur, Kuala Lumpur, Malaysia

Outcomes

Primary Outcomes

Improvement in Child-Pugh score

Change in the Child-Pugh score, assessing liver damage in cirrhosis

Time frame: Up to 6 weeks

Secondary Outcomes

Improvement in nutritional parameters

Improvement in nutritional anthropometry and assessment tool markers after intervention

Time frame: up to 6 weeks

Data from ClinicalTrials.gov

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