The purpose of this trial is to determine the safety and tolerability of ascending single and multiple oral doses of LEO 27847 in secondary hyperparathyroidism patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
72
First in patient
CRS Clinical Research Services Kiel GmbH
Kiel, Germany
Centralny Szpital Kliniczny MON
Warsaw, Poland
Safety and Tolerability
Adverse events, vital signs, ECG, laboratory evaluation, physical examination
Time frame: 7 days after last dosing
Pharmacokinetics and Pharmacodynamics
LEO 27847, PTH, calcium, Vitamin D and phosphate in blood. LEO 27847 in urine
Time frame: 7 days after last dosing
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