Fluid Balance and Clinical Outcomes

University of Florida300 enrolled

Overview

This study is about investigating the relationship of postoperative fluid balance, inflammation and acute kidney injury. This is a non-interventional study (no drug administration). The investigators will collect baseline demographic data, postoperative fluid balance status by Intake-output data, follow routine labs and collect 1 blood sample (0.5ml) with morning lab draws on day 1 and 5ml urine samples on day 1 and 2.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Fluid Balance Input and Output Inflammatory Mediators Acute Kidney Injury Mortality

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 years or older, and * Undergoing elective cardiothoracic surgery(s), alone or in combination with other procedures/surgery(s): thoracic aortic aneurysm, cardiac valves, coronary artery bypass grafting, abdominal thoracic aneurysm, and other cardiovascular surgery. Exclusion Criteria: * Pregnancy * History of any organ transplant * Preoperative intra-aortic balloon pump (IABP) * Current use of natriuretic peptides * ESRD patients on dialysis * Estimated GFR \< 30ml/min using MDRD equation.

Locations (1)

Shands Hospital, University of Florida

Gainesville, Florida, United States

Data from ClinicalTrials.gov

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