Effects of Levetiracetam (Keppra) on Alcohol Consumption

Inclusion Criteria: 1. Healthy adults who are social drinkers 21 and 50 years of age. 2. Moderate to heavy social drinkers (women=7-21 drinks/week, men=7-25 drinks/week). 3. Body Mass Index (BMI)\>18 and \<30. 4. If female, must be non-lactating, not pregnant, and using a reliable contraception method (i.e. abstinence, intrauterine device \[IUD\], hormonal birth control, or double barrier method \[male condom, female condom, or diaphragm plus a spermicidal agent such as contraceptive foam, jelly or cream\]). 5. Able and willing to provide written informed consent. 6. Able to understand and follow the instructions of the investigator, and understand all rating scales. 7. Have a negative urine drug screen at all visits, with the exception of cannabinoids. Exclusion Criteria: 1. Positive urine drug screen, except cannabinoids. Occasional cannabinoid use is allowed, however daily use, dependence, or if considered more than a casual user by study physician, subject will be excluded. 2. Use of cocaine, amphetamines or other stimulants, hallucinogens, ecstasy or other psychoactive drugs, greater than 10 times in the last 24 months or at anytime in the past 60 days. 3. Lifetime use of PCP or ketamine greater than 10 times, or at any time in the last 24 months. 4. History of abusing inhalants (such as glue, toluene or other volatile substances). 5. Current or past dependence on, or addiction to any psychoactive drug (except nicotine or caffeine) including alcohol, as determined by the study physician's assessment. 6. Current or prior enrollment in an alcohol or other drug treatment program, or current legal problems relating to alcohol or other drug use, including awaiting trial or supervision by a parole or probation officer. 7. Binge drinking more than three times per week (binge defined as \>5 standard drinks in one session). 8. Alcohol consumption \>21 drinks/week for women and \>25 drinks/week for men. 9. Currently trying to quit alcohol and/or recreational drug use. 10. Positive for lifetime abnormal opioid use or prescription drug abuse. 11. Clinically significant medical or psychiatric illness (including anxiety or panic disorders) as determined by screening blood tests, medical history, and physical exam performed or reviewed by the study physician. 12. Bilirubin more than 2 times the normal upper limit. 13. AST (SGOT), ALT (SGPT), or alkaline phosphatase more than 2 times the normal upper limit. 14. Body Mass Index \>30 or \<18 15. Pregnancy or a woman of child bearing potential not currently using an adequate means of contraception. 16. Currently taking any medication other than over-the-counter nonsteroidal anti-inflammatories, acetaminophen, inhaled asthma therapy, contraceptives, nicotine patches, and over-the-counter non-sedating antihistamines.NSAIDs, acetaminophen, or any other OTC (including herbal) medication (unless cleared by study physician). 17. BAC level greater than 0.02% at the beginning of visits 1, 7, or 8 (within margin of error for detection). 18. Estimated creatinine clearance \< 50 ml/min. 19. Chronic pain condition requiring regular physician visits and treatment under a physician's supervision. 20. Neurological dysfunction or psychiatric disorder severe enough to interfere with assessment of outcome measures as defined above. 21. Allergy to levetiracetam. 22. Significant cardiac pathology or abnormal initial EKG with QT/QTc interval prolongation \> 480 m secs at baseline. 23. Has received an investigational drug within 30 days prior to Study Visit 2 (after screening visit). 24. Subjects who are unable to read or speak English. 25. Those, in the opinion of the investigator, who are considered unable to adhere to scheduled appointments, unlikely to comply with the study protocol, or who are unsuitable for any other reason.