The purpose of this prospective, participant-blinded trial is to determine the changes in sleep architecture in a cohort of subjects who have undergone deep brain stimulation (DBS) surgery for treatment of movement disorders such as moderate to advanced Parkinson's disease (PD), tremor, or dystonia. Our preliminary observational data suggest that unilateral subthalamic nucleus (STN) DBS improves subjective sleep quality in PD patients 6 months after the procedure. The cause of this improvement in sleep quality is unknown, and this study proposes the use of polysomnography (PSG) to test whether the improvement in sleep is independent of improvement in night-time mobility associated with DBS treatment of the motor symptoms of PD, tremor, or dystonia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
17
Alteration of DBS stimulator settings
University of Alabama at Birmingham
Birmingham, Alabama, United States
Sleep Efficiency
This is the percentage of time the subject is in bed when he/she is actually asleep.
Time frame: 1 month
Wake after sleep onset (WASO)
This is a measurement of the amount of time during polysomnography recording that the subject is awake after their initial sleep onset.
Time frame: 1 month
Total Sleep Time
Time frame: 1 month
Two timed motor tasks
1. The subject will tap index finger between 2 points 30 cm apart on the table for 10 seconds. 2. The subject will be timed as they rise from a chair, walk 7 meters, return to the chair, and sit down.
Time frame: 1 month
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