The aim of this prospective randomized controlled study was to compare the prophylactic effects of intravenous single dose of ondansetron, ramosetron, and palonosetron on PCA-related nausea and vomiting after urologic laparoscopic surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
105
Ondansetron/single injection/4 mg/IV
Ramosetron HCl/single injection/0.3mg/IV
Palonosetron HCl/single injection/0.075mg/IV
Severance Hospital, Yonsei University College of Medicine
Seoul, South Korea
severity of nausea
Time frame: during 73 hours after surgery
the number of vomiting
Time frame: during 73 hours after surgery
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normal saline injection 2ml