Intranasal Ketamine Versus Intramuscular Ketamine for Procedural Sedation in Pediatric Patients

University of Iowa3 enrolled

Overview

The purpose of this study is to determine if intranasal ketamine is equally as effective and safe as intramuscular ketamine for procedural sedation in pediatric patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Sedation

Interventions

KetamineDRUG

Intranasal Ketamine (100 mg/mL)

KetamineDRUG

Intramuscular Ketamine

Eligibility

Sex: ALLMin age: 2 YearsMax age: 17 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * pediatric patients age 2 to 17 years old * have a laceration of 4 cm on the face or 7 cm on the remainder of the body * Require procedural sedation to repair the laceration Exclusion Criteria: * Patients with abnormal nasal physiology which would not allow for adequate medication delivery * Unable to have a guardian present to consent on their behalf * Allergy to ketamine * Significant cardiac history (myocardial ischemia, heart failure, arrhythmias) * Presenting with a head injury associated with possible intracranial hypertension * Pregnancy * Lacerations that require repair from a consult service

Locations (1)

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States

Outcomes

Primary Outcomes

Onset of Sedation

Minutes it takes until the patient is cooperative enough for the procedure

Time frame: Every 60 seconds through study completion

Data from ClinicalTrials.gov

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