Efficacy Evaluation of Surfactant Administration Via Laryngeal Mask Airway

Inclusion Criteria: * Birthweight more than 1000 grams * Gestational age more than 28 weeks and less than 35 weeks * Chronologic age less than 8 hours * Diagnosis of RDS by clinical and radiographic criteria * Treated with nasal continuous positive airway pressure and supplemental oxygen more than 30% * Parental consent Exclusion Criteria: * Birthweight less than 1000 grams * Gestational age more than 28 weeks and less than 35 weeks * Chronologic age more than 8 hours * Maternal fever or premature rupture of fetal membranes less than 18 hours * Diagnosis other than respiratory distress syndrome * Babies who require or have already had endotracheal intubation * Analgesia and or sedation during the first six hours of life * Apgar 5 minute score less than three * Babies with congenital anomalies or signs of acute circulatory failure