Persistence of Rabies Antibody 1-5 Years After the Post-exposure Prophylaxis With Vero Cell Antirabies Vaccine and Antibody Response to a Single Booster Dose

Peking University People's Hospital160 enrolled

Overview

This study is to investigate the persistence of rabies Chinese manufactured antibody 1-5 years after the post-exposure prophylaxis with vero cell antirabies vaccine and antibody response to a single booster dose. A total of 160 subjects would be enrolled. These subjects were all administered ChengDa antirabies vaccine from 2005 to 2009. After informed consent is obtained, these subjects would be tested for their antirabies antibody titer and given a single booster dose. Seven and 14 days later, the investigators would re-evaluate the antibody titer.

Study Type

INTERVENTIONAL

Allocation

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

160

Conditions

Rabies

Interventions

Rabies vaccine, manufactured by ChengDa

1 dose before the antibody is tested

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 20 to 60 years old * Healthy * Given ChengDa rabies vaccine * Good compliance * Obtained informed consent Exclusion Criteria: * Other than inclusion criteria

Locations (1)

Peking University People's Hospital

Beijing, Beijing Municipality, China

Outcomes

Primary Outcomes

Rabies antibody titer

We test the antirabies antibody titer before and after the single booster dose

Time frame: 6 months

Data from ClinicalTrials.gov

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