The purpose of the study is to compare a fish oil containing lipid emulsion against a medium-chain/long-chain triglyceride (MCT/LCT) lipid emulsion in terms of their efficacy and safety during postoperative parenteral nutrition.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
240
medium chain triglycerides, long chain triglycerides, omega-3 fatty acid containing triglycerides
medium chain triglycerides, long chain triglycerides
Hospitals
Beijing, China
Nanjing Hospital
Nanjing, China
To investigate on the efficacy of fish oil on the nutrition status
Prealbumin as the primary endpoint variable
Time frame: day 1 to day 6
To investigate on the efficacy of fish oil on an inflammatory parameter
LTB5/LTB4 as a second primary endpoint
Time frame: day 1 to day 6
Incidence of postoperative complications
Time frame: 6 days
Liver function
Time frame: 6 days
Coagulation parameters
Time frame: 6 days
Blood chemistry
Time frame: 6 days
SIRS
Time frame: 6 days
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