Many stress tests being done today have two parts, the stress test and the pictures of your heart. The investigators are comparing a newer technique to obtain the pictures (PET imaging) to the standard method (SPECT imaging). However, it is not known if the new test is better than the old test. It is important to have a standard to compare these tests to, and that is why people who will be getting a cardiac catheterization are being asked to participate. The information about your arteries from the cardiac catheterization will be used to judge which stress test is better. The investigators hypothesize that the newer method (PET imaging) will be more accurate than the old method (SPECT) in detecting heart disease.
A SPECT rest image will be obtained using a technetium based isotope. On a separate day, a Rubidium rest PET image will be obtained prior to a Dipyridamole stress test. Subjects will receive both Rubidium and technetium isotopes following the Dipyridamole stress, and will undergo first PET imaging and later SPECT imaging following the stress test. Patients will then go for cardiac catheterization as clinically ordered by their physician.
Study Type
OBSERVATIONAL
Enrollment
136
Dipyridamole stress testing 0.57 mg/kg
Dipyridamole stress test 0.57 mg/kg with Rubidium PET images
The Heart Center, PC
Huntsville, Alabama, United States
Hartford Hospital
Hartford, Connecticut, United States
Cardiovascular Imaging Technologies, LLC
Kansas City, Missouri, United States
Sanford Health Clinical Research
Fargo, North Dakota, United States
Ohio Health Research Institute
Columbus, Ohio, United States
Coronary Artery Disease
Time frame: 30 days
Myocardial Ischemia
Time frame: 30 days
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