Diagnostic Utility of Pleural Fluid MAGE Assay in Patients With Pleural Effusion From Primary Lung Cancer

Samsung Medical Center100 enrolled

Overview

Melanoma antigen (MAGE) gene is known to be expressed in tumor cells, testis and placenta. The purpose of this prospective study was to investigate the sensitivity, specificity and accuracy of pleural fluid MAGE gene expression, tumor marker and cytology in the diagnosis of malignant pleural effusion.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

100

Conditions

Unilatral Pleural Effusion

Interventions

pleural fluid tappingPROCEDURE

Minimally invasive technique to detect malignant pleural effusion

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * unilateral pleural effusion on chest radiography Exclusion Criteria: * body temperature \> 38.3ºC and peripheral blood leukocytosis (\>12,000/μl)

Locations (1)

Samsung Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

The purpose of this prospective study was to investigate the sensitivity, specificity and accuracy of pleural fluid MAGE gene expression, tumor marker and cytology in the diagnosis of malignant pleural effusion.

Time frame: 12months interval

Data from ClinicalTrials.gov

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