Thickness of Retinal Layers in Amblyopia

Samsung Medical Center22 enrolled

Overview

The purpose of this study is to examine retinal layer thickness in amblyopia.

Amblyopia is a visual disorder characterized by a reduction of vision that cannot be immediately improved by refractive correction or accounted for by clinically determined anatomic defects of the eye or visual pathway. Evidence for direct retinal changes in eyes with amblyopia has been controversial. It has been hypothesized that amblyopia may affect the postnatal maturation of the retina including the postnatal reduction of retinal ganglion cells. However, although some studies have found incrased retinal nerve fiber layer thickness in amblyopic eyes, others have found no significant differences. This sutdy will examine the retinal layer thickness in amblyopia and compare the retinal layer thickness between amblyopic eyes and nonamblyopic fellow eyes.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Amblyopia

Interventions

Optical coherence tomographyOTHER

Spectral domain optical coherence tomography will be conducted once when patients are enrolled.

Eligibility

Sex: ALLMin age: 4 YearsMax age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Amblyopia Exclusion Criteria: * Other retinal disease * Anisometropia * Neurologic abnormalities

Locations (1)

Samsung Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

Retinal layer thickness

Optical coherence tomography scan will be conducted to analyze retinal layer thickness, when the patient are enrolled.

Time frame: One month

Data from ClinicalTrials.gov

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