Superselective IRA infusion of tirofiban may improve myocardial reperfusion and reduce bleeding complications in AMI patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
a bolus of 10ug/kg tirofiban administration via thrombus aspiration catheter followed by 0.1ug/kg/min for 12 hours after PCI
a bolus of 10ug/kg tirofiban administration via guide catheter followed by 0.1ug/kg/min for 12 hours after PCI
the 28th division, Beijing Anzhen Hospital
Beijing, Beijing Municipality, China
RECRUITINGMajor adverse cardiovascular events
Infarct size, reinfarction, motality, et.al.
Time frame: 1 month after PCI
Major adverse cardiovascular events
Infarct size, reinfarction, motality, et.al.
Time frame: 3 months after PCI
Major Adverse Cardiovascular Events
Infarct size, reinfarction, motality, et.al.
Time frame: 6 months after PCI
number of participants with bleeding events
bleeding events are assessed by Thrombolysis In Myocardial Infarction(TIMI) criteria
Time frame: 1 month
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.