Acute Lung Injury After Aortic Valve Surgery

University of Oulu100 enrolled

Overview

The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery. Study questions: * Is there any correlation between the release of pro-inflammatory biomarkers and lung injury degree? * Is there any correlation between oxyhaemodynamic parameters and lung injury degree? * Is there any correlation between oxyhaemodynamic parameters and the release of pro-inflammatory biomarkers? * Are budesonide, erdostein and acetylcystein effective in the prevention of lung injuries?

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Lung Injury

Interventions

aortic valve surgery with CPBPROCEDURE

elective aortic valve surgery with CPB

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * elective aortic valve surgery patient * written consent Exclusion Criteria: * none

Locations (1)

Oulu University hospital

Oulu, Finland

Outcomes

Primary Outcomes

lung injury

Time frame: within the first 3 days after surgery

Central Contacts

Fausto Biancari, MD, PhD

CONTACT

fausto.biancari@ppshp.fi

Data from ClinicalTrials.gov

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