Project PREVAM : Prospective Comparison of Capsule Endoscopy Pillcam II™ Versus Colonoscopy

Inclusion Criteria: * Age \> 18 years old * Patient with 40 years old and first degree relative affected by colo rectal cancer at age ≥ 60 ans * Patient with 40 years old or ten years before the age at affected disease in case or first deree relative colo rectal cancer before 60 years old. * Fecal occult blood test positive * Personal history of adenomatous polyps * Personnal history of acromegaly * Patient with social insurance * Persons already participating in another clinical trial.. * Signature of informed consent Exclusion Criteria: * Pregnancy or breast feeding woman * Déficience mentale du sujet rendant sa participation à l'essai impossible * Pacemaker or all electronic devices implanted * Patient with swallowing disorder, or digestive stricture know or suspected by the investigator * Previous history of intestinal surgery, radiotherapy or inflammatory bowel disease * Previous history of polyadenomatous congenital disease, Lynch syndrome * Intolerance with dompéridon and/or bisacodyl * Intolerance with oral intake of NaP, polyethylen glycol (PEG) or macrogol * Colonoscopy contre indication for anesthesiologic reasons