Accelerated Partial Breast Irradiation by Mammosite and intensity modulated radiotherapy is safe and effective in patients with early stage breast cancer resected by lumpectomy.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
291
Treatment will be performed using high dose rate brachytherapy, starting between 2-5 days of implant, 34 Gy at 1 cm in 3.4 Gy fractions BID for 5 treatment days with typical boost dose od 10 Gy given in 2 fractions at least 6 hours apart.
Accelerated Partial Breast Irradiation using intensity modulated radiotherapy, a novel planning and delivery technique for external beam radiation
Rocky Mountain Cancer Centers - Aurora
Aurora, Colorado, United States
Rocky Mountain Cancer Centers - Boulder
Boulder, Colorado, United States
Rocky Mountain Cancer Centers - Midtown
Denver, Colorado, United States
Rocky Mountain Cancer Centers - Littleton
Littleton, Colorado, United States
Overall Survival
Time frame: 2-15 years
Disease free survival
Time frame: 2-15 years
Cause specific survival
Time frame: 2-15 years
Ipsilateral breast failure
Time frame: 2-15 years
Serious Adverse device-related Events
Time frame: 2-5 years
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Rocky Mountain Cancer Centers - Sky Ridge
Lone Tree, Colorado, United States
Rocky Mountain Cancer Centers - Thornton
Thornton, Colorado, United States