The Effects of a Ficus Carica on Improvement in Bowl Movements in Female Volunteer With Functional Constipation

Inclusion Criteria: * Subjects who are female volunteers (unmarried), 19\~40 years * Subject who have functional constipation by ROME IIII criteria * Subject who have over 36 hour colonic transit time * Subject must provide written informed consent to participate in the study Exclusion Criteria: * Subject with a history or evidence of clinically significant gastrointestinal, anorectal, hepatic, renal, neurological, pulmonary, endocrine, blood tumor, psychiatric, Cardiovascular disease * Subjects who have a gastrointestinal (GI) disease (Crohn's disease, etc.) that would increase the influence with absorbance medication or a GI surgery excluding appendectomy and hernia surgery * Subject with uterine fibroids at ultrasonography * Subject is pregnant, planning to become pregnant, or breast-feeding * Subjects with childbearing potential (i.e. pre-menopausal, not surgically sterile) not willing to use a medically accepted contraceptive (oral contraception) regimen * Known history of moderate to severe hepatic impairment (i.e., serum ALT\>1.5×ULN, AST\>1.5×ULN) * Subjects with uncontrolled hypotension (indicated by a sitting systolic blood pressure ≤ 95 mmHg or diastolic blood pressure ≤ 60 mmHg measured) and hypertension (indicated by a sitting systolic blood pressure≥ 150 mmHg or diastolic blood pressure≥ 95 mmHg measured) at vital sign measurement * Subjects with significant hypersensitivity about Ficus carica * Subjects who received certain medications that cause the alteration of bowel movement within the past 2weeks prior to first administration * Subjects who participated in other clinical investigation within 2 months prior to first administration * Subject who drink constantly (21 units/week over) * Subject who have Irritable bowel syndrome by ROME IIII criteria * Any significant condition that, in the opinion of the investigator, could interfere with the subject's participation or compliance in the study (i.e., laboratory test and others)