Athletic tendinopathies of the upper and lower extremity are often therapeutically challenging. Colour and Power-Doppler-ultrasound visualizes pathological neovessels in painful tendons, which are associated with pain-mediating nerve fibres in such tendinopathies. These neovessels are represented by an increased capillary blood flow at the point of pain. Painful eccentric training reduces pain and improves function in Achilles tendinopathy substantially (evidence level Ib). Shock wave therapy in combination with eccentric training is superior to eccentric training alone (evidence level Ib). Long-term results suggest a collagen induction and reduced pain following topical glyceryl trinitrate (NO) (evidence level Ib). Colour- and Power-Doppler-guided sclerosing therapy using polidocanol reduces pain, improves function and may lead to tendon remodelling (evidence level Ib). Pain-restricted sport beyond pain level 5/10 during therapy is recommended (evidence level Ib). 3x10min of cryotherapy reduce pain and capillary blood flow (evidence level Ib). The role of proprioceptive training in tendinopathy has to be determined in future randomized-controlled trials (evidence level II). The investigators thought to evaluate the combination of the aforementioned individually successfully therapeutic options in athletes to shorten the recovery period and return to play interval.
Interventions: Combined Power-Doppler-guided sclerosing therapy using Polidocanol (0.5%, 2ml) in 6-8 week intervals combined with extracorporeal focused shockwave therapy (STORZ Duolith 2000impulses 0.25mJ/mm2) every 6-8weeks plus painful daily eccentric training plus daily topical NO
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
114
Power-Doppler-guided extratendinous sclerosing therapy using Polidocanol 0.5% up to 2ml every 6-8 weeks
Focused extracorporeal shock wave therapy using a STORZ Duolith machine 2000 Impulses 0.25mJ/mm2 every 6-8 weeks
Topical nitroglycerine (Nitrolingualspray(R)) 2x2 hubs per day over 6 months daily on the painful tendon
Painful eccentric training for Achilles tendinopathy on a stair single-stance with 6x15 repetitions per leg and day over at least 12 weeks
Painful eccentric training for patella tendinopathy on a 25° decline board single-stance with 6x15 repetitions per leg and day over at least 12 weeks
Painful eccentric training for elbow tendinopathy using a green coloured Thera-Band Flex-Bar with painful supination and pronation with 6x15 repetitions per day over at least 12 weeks
Hannover Medical School, Plastic, Hand and Reconstructive Surgery
Hanover, Germany
Functional impairment of the Achilles tendon using VISA-A score [0=worse, 100=perfect]
Score of patient-related outcome measure: Achilles tendon: VISA-A \[0=worse, 100=perfect\] derived from eight validated questions on pain and function during activities of daily living
Time frame: up to 4 years
Functional impairment of the patella tendon according to the VISA-P score [0=worse, 100=perfect]
Score of patient-related outcome measure: Patella tendon: VISA-P \[0=worse, 100=perfect\] derived from eight validated questions on pain and function during daily activities
Time frame: up to 4 years
Functional impairment due to epicondylitis measured by the DASH score [0=perfect, 100=worse]
Score of patient-related outcome measure: Epicondylitis: DASH score \[0=perfect, 100=worse\] derived from 30 validated questions regarding the impairment in activities of daily living
Time frame: up to four years
Pain level at rest [VAS 0-10]
Time frame: up to 4 years
Pain level at exertion [VAS 0-10]
Time frame: up to 4 years
Patient satisfaction on Likert scale [1-6]
Patient satisfaction on Likert scale from 1=perfect, wholy satisfied, to 6=worst, dissatisfied
Time frame: up to 4 years
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