The purpose of this study is to establish the safety and effectiveness of coronary stenting with the Zotarolimus-Eluting stent compared to the Sirolimus-Eluting stent in the treatment of de novo coronary stenosis in patients with diabetic patients.
Prospective, two arms, single blind, randomized multi-center trial of 380 patients enrolled at 24 centers in Korea. Following angiography, diabetic patients with significant diameter stenosis \>50% by visual estimation have documented myocardial ischemia or symptoms of angina, and eligible for stenting without any exclusion criteria will be randomized 1:1 to: a) Endeavor Resolute stent vs. b) Cypher select. All patients will be followed for at least 1 year. Angiographic follow-up at 9-months is routinely recommended.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
256
zotarolimus-eluting stent
sirolimus-eluting stent
Hallym University Sacred Heart Hospital
Anyang-si, Gyeonggi-do, South Korea
Soonchunhyang University Bucheon Hospital
Bucheon-si, South Korea
Soonchunhyang University Cheonan Hospital
Cheonan, South Korea
Angiographic in-segment late loss
Time frame: 9-month angiographic follow-up
Death (all-cause and cardiac)
Time frame: at 12 months
myocardial infarction
Time frame: at 12 months
stent thrombosis
Time frame: at 12 months
target-lesion revascularization
Time frame: at 12 months
target-vessel revascularization
Time frame: at 12 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Kangwon University Hospital
Chuncheon, South Korea
Daejeon St Mary's Hospital Catholic University
Daejeon, South Korea
GangNeung Asan Hospital
Gangneung, South Korea
Chonbuk National University Hospital
Jeonju, South Korea
Pusan National University Yangsan Hospital
Pusan, South Korea
Asan Medical Center
Seoul, South Korea
Seoul Veterans Hospital
Seoul, South Korea
...and 1 more locations