This randomized study is a multi-center, randomized, study to compare the efficacy of biolimus A9-eluting stent (Nobori) vs. everolimus-eluting stent (Promus Element) for long coronary lesions.
Following angiography, patients with significant diameter stenosis \>50% and lesion length(\> 25mm) requiring single or multiple long-stent placement(total stent length 28mm) by visual estimation and eligible for LONG-DES V trial inclusion and exclusion criteria will be randomized 1:1 to a) NOBORI and b) PROMUS-ELEMENT stent by the stratified randomization method.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
500
drug-eluting stent
drug-eluting stent
Soonchunhyang University Hospital, Buchen
Bucheon-si, South Korea
Soonchunhyang University Cheonan Hospital
Cheonan, South Korea
Kangwon National University Hospital
Chooncheon, South Korea
In-segment late luminal loss
Time frame: 9 month angiographic follow-up
Death (all-cause and cardiac)
Time frame: 1 year
Myocardial infarction
Time frame: 1 year
stent thrombosis(ARC criteria)
Time frame: 1 year
target-lesion revascularization
Time frame: 1 year
target-vessel revascularization
Time frame: 1 year
Procedural success
Time frame: at 1 day
Death (all-cause and cardiac)
Time frame: one month
Death (all-cause and cardiac)
Time frame: 9 months
Myocardial infarction
Time frame: one month
Myocardial infarction
Time frame: 9 months
Composite of death or MI
Time frame: one month
Composite of death or MI
Time frame: 9 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Daegu Catholic University Medical Center
Daegu, South Korea
Keimyung University Dongsan Medical Center
Daegu, South Korea
Kyungpook National University Hospital
Daegu, South Korea
NHIC Ilsan Hospital
Ilsan, South Korea
Dong-A University Medical Center
Pusan, South Korea
Inje University Pusan Paik Hospital
Pusan, South Korea
Asan Medical Center
Seoul, South Korea
...and 1 more locations
Composite of death or MI
Time frame: 1 year
Composite of cardiac death or MI
Time frame: one month
Composite of cardiac death or MI
Time frame: 9 months
Composite of cardiac death or MI
Time frame: 1 year
target-lesion revascularization
Time frame: one month
target-lesion revascularization
Time frame: 9 months
target-vessel revascularization
Time frame: one month
target-vessel revascularization
Time frame: 9 months
stent thrombosis(ARC criteria)
Time frame: one month
stent thrombosis(ARC criteria)
Time frame: 9 months
In-stent late loss
Time frame: 9 month angiographic follow-up
8. Target-vessel failure (death from any cause, myocardial infarction, and ischemic-driven target-vessel revascularization)
Time frame: 12 months
In-stent and in-segment restenosis
Time frame: 9 month angiographic follow-up
Angiographic pattern of restenosis
Time frame: 9 month angiographic follow-up