STUDY: Effects of Potatoes in a Weight Loss Program

University of California, Davis90 enrolled

Overview

The purpose of this study is to test whether diets that contain potatoes and differ in glycemic index/load will be useful in weight loss, blood sugar control and maintaining current body weight.

The study will examine the effect of including potatoes as part of a calorie restricted diet designed to induce weight loss and improve glycemic control in overweight subjects. This is a randomized, treatment-controlled, 3-arm, parallel study. The 3 arms of the study will include dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). Two diets will be energy-restricted (\~ 500 kcal deficit /d) for weight loss and the control diet will be prescribed for weight maintenance. The two energy-restricted diets will include further manipulation, such that, one dietary plan will be a high glycemic index (GI) diet and the other a low glycemic index diet.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Obesity

Interventions

ControlBEHAVIORAL

Dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). The control diet will be prescribed for weight maintenance.

Low Glycemic IndexBEHAVIORAL

Diets will be energy-restricted (\~ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on Low Glycemic Index foods.

High Glycemic IndexBEHAVIORAL

Diets will be energy-restricted (\~ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on Low Glycemic Index foods.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Men and women * ≥ 18 years of age who have a body mass index (BMI) of 25 to 35 kg/m2 (inclusive). Exclusion Criteria: * Total cholesterol (TC) not greater than 300 mg/dL, * Fasting triglyceride not greater than 300 mg/dL , * LDL cholesterol (LDL-C) not greater than 180 mg/dL, * Smokers * Female subjects who are pregnant or lactating * Subjects taking any medications that would interfere with outcomes of the study * Subjects with unusual dietary habits (eg., pica) * Subjects who are actively losing weight or trying to lose weight * Subjects who are addicted to drugs or alcohol or who are \< 1 y in recovery program * Subjects who present with significant psychiatric or neurological disturbances * Subjects with known allergy or intolerance to potato products * Subjects with documented atherosclerotic disease, inflammatory disease, diabetes mellitus, uncontrolled hypertension ( 140/90 mm Hg), chronic lung, renal or liver disease

Locations (2)

University of California Davis (Academic Surge, Ragle Human Nutrition Research Facility)

Davis, California, United States

VA Hospital, Mather

Mather, California, United States

Outcomes

Primary Outcomes

Weight Loss

Time frame: 12 Weeks

Secondary Outcomes

Glucose tolerance

Time frame: 12 Weeks

Body composition

Time frame: 12 weeks

Blood Pressure

Time frame: 12 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.