Lung Perfusion With Oxygenated Blood During Aortic Clamping

Johann Wolfgang Goethe University Hospital50 enrolled

Overview

Pulmonary dysfunction presumably linked to an inflammatory response is frequent after cardiac operations using cardiopulmonary bypass (CPB) and pulmonary hypoperfusion. Aim of the study: To evaluate the protective effect of continuous pulmonary perfusion with oxygenated blood during aortic crossclamping on the inflammatory response.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Postoperative Pulmonary Dysfunction

Interventions

lung perfusionPROCEDURE

see literature of proceeding

no lung perfusionPROCEDURE

see literature of proceeding

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-80 ys * Cardiopulmonary bypass procedure * FEV1 \<80% * COPD \>II Exclusion Criteria: * Emergency cases

Locations (1)

Goethe University

Frankfurt am Main, Germany

Outcomes

Primary Outcomes

Inflammatory marker

Time frame: 5 days

Data from ClinicalTrials.gov

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