The study will be conducted as an open label, single-dose, explorative study with patients with histologically proven cancer and, preferably, tumor positive lesions in previously performed nuclear medicine imaging examinations. The investigational drug will be given as a single administration in a dose of \</= 0.1 mg BAY94-9392 (300 MBq, +/- 10%). The total duration of the study for each patient will be approximately 8 days.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
30
A radioactive dose of 300 MBq of the study drug with a total quantity of \</= 0.1 mg will be administered as slow intravenous bolus injection over up to 60 seconds
Unnamed facility
Stanford, California, United States
Evaluation of the accumulation of BAY94-9392 in primary cancer lesions confirmed by histology.
Time frame: Day 1
Evaluation of the accumulation of BAY94-9392 in known or suspected local and/or systemic recurrent cancer lesions and/or lymph node metastasis or distant metastasis.
Time frame: Day 1
Standardized uptake value (SUV)
Time frame: Day 1
Standardized uptake value ratio (SUVR)
Time frame: Day 1
Vital Signs
Time frame: Day 1 and Day 2
Laboratory Findings
Time frame: Day 1 and Day 2
Electrocardiograms (ECGs)
Time frame: Day 1 and Day 2
Adverse Event Collection
Time frame: Day 1 and Day 2
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