The purpose of this study is to evaluate the pharmacokinetics (PK) and safety following oral administration of ASP1941 in subjects with moderate hepatic impairment and in subjects with normal hepatic function based on the Child-Pugh Classification (CPC).
Study drug will be orally administered on Day 1. Subjects will be admitted to the clinic until completion of clinic discharge procedures on Day 7 with an outpatient follow-up visit 6-9 days after clinic discharge.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Masking
NONE
Enrollment
16
oral
Unnamed facility
Miami, Florida, United States
Pharmacokinetic variables used to assess the effect of hepatic function through analysis of blood samples
Time frame: 7 days following study drug administration
Pharmacokinetic variables used to assess the effect of hepatic impairment through analysis of blood and urine samples
Time frame: 7 days following study drug administration
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