Full-dose Atorvastatin After Acute Coronary Syndrome (ACS) in Non-revascularisable Coronary Artery Disease

Inclusion Criteria: * non-ST-segment elevation acute myocardial infarction. * coronary angiography within 48 hours from admission. * angiographic evidence of severe and diffuse coronary artery disease,not amenable to conventional direct revascularisation techniques by coronary artery bypass graft (CABG) or percutaneous coronary intervention (PCI). Exclusion Criteria: * ST-segment elevation acute myocardial infarction, * clinical history of heart failure * left ventricular ejection fraction \<35%, * any form of severe valvular dysfunction, * previous implantation or indication to implant a cardioverter-defibrillator during the index admission, * any increase in liver enzymes, * history of any liver or muscle disease, * renal failure with serum creatinine \>2.5 mg/dL (221 mmol/L), * need for continued use of intravenous medications to relieve anginal symptoms, * presence of any major comorbidity with life expectancy \<24 months.