Optimal Endotracheal Cuff Pressure During Hospitalization in Intensive Care Units Using AnapnoGuard 100 System

Inclusion Criteria: * Age above 18 (men and woman); * Patient is admitted to ICU and expected to receive mechanical ventilation for at least 48 hours; * Normal chest X-ray; * Connection of the ETT to the AnapnoGuard system less than 6 hours from intubation initiation; * Signed informed consent by subject's legally acceptable representative. Exclusion Criteria: * Patients who had been treated with mechanical ventilation during the last year; * Fever from known chest/lung origin; * Patients with facial, oropharyngeal or neck trauma; * BMI\>35; * Height \< 1.6 m; * Any chest X-ray pathology during the first 24 hours post intubation; * More than 7 days hospitalization prior to the intubation. Chest/lung infection.