Obesity is now becoming significantly prevalent of an environment characterized by easily available calorics foods combined with sedentary lifestyles. Moreover, it has been demonstrated that obesity is associated with metabolic complications such as disturbed adipocytokines, hormones secreted by adipose tissue. Given these observations, the purpose of this study is to assess the effects of a lifestyle intervention focused on various physical activities and nutrition education on adipocytokines hormones, in severely obese teenagers.
Study Type
OBSERVATIONAL
Enrollment
32
physical activity 5 times per week + nutrition education
Centre Hospitalier Universitaire
Besançon, France
Adipocytokines (leptin, adiponectin, ghrelin, PAI-1, resistin), based on subject's arterialized capillary blood samples.
Time frame: during a lifestyle intervention of 9 months
Body weight, body mass index, waist and hip circumference
Time frame: during a lifestyle intervention of 9 months
Body composition, calculated by a multifrequency bioelectric impedance
Time frame: during a lifestyle intervention of 9 months
Glycemia and lipids profile, based on subject's arterialized capillary blood samples analysis.
Time frame: during a lifestyle intervention of 9 months
Insulin resistance, calculated according to the formula of homeostasis model assessment
Time frame: during a lifestyle intervention of 9 months
Systolic and diastolic blood pressure, measured in millimeters of mercury at the level of the left brachial artery, using an automatic blood pressure monitor.
Time frame: during a lifestyle intervention of 9 months
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