The purpose of this study is to evaluate the efficacy of ultraviolet-A (UVA)-induced cross-linking of corneal collagen (CXL) as a method to increase the biomechanical and biochemical stability of the cornea by inducing additional cross-links within or between collagen fibers using UVA light and the photo- mediator riboflavin. The purpose of this study is to generate data for presentation at medical meetings and for peer-review publication. The data generated by this study will not be submitted to the FDA to support commercialization of these riboflavin drops.
Study Type
OBSERVATIONAL
Enrollment
3,493
Ciprofloxicin or Vigamox or other to be used qid till epithelialized.
Nonsteroidal (Acular, Voltaren Xibrom, etc) qid up to 5-10 days post-op
Steroid (FML, Pred Forte, Flarex, etc.) to be used qid to qd for 1-8 weeks.
Schwartz Laser Eye Center
Scottsdale, Arizona, United States
Harvard Eye Associates
Laguna Hills, California, United States
Clear View Eye & Laser Medical Center
San Diego, California, United States
Unnamed facility
San Francisco, California, United States
Davidorf Eye Group
West Hills, California, United States
Corneal Consultants of Colorado, P.C
Littleton, Colorado, United States
The Center for Excellence in Eye Care
Miami, Florida, United States
Chicago Cornea Consultants, LTD
Hoffman Estates, Illinois, United States
TLC Laser Eye Center
Rockville, Maryland, United States
Talamo Laser Eye Center
Waltham, Massachusetts, United States
...and 6 more locations
Increase the biomechanical and biochemical stability of the cornea by inducing additional cross-links within
Time frame: 1 year
increase the biomechanical and biochemical stability of the cornea between collagen fibers using UVA light and the photo- mediator riboflavin
Time frame: 1 year
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