Laser Based Focal Ablation of Low Grade Prostate Cancer

Inclusion Criteria: * Male, 45 years of age or older * Diagnosis of prostate adenocarcinoma * Clinical stage T1c or T2a * Gleason score of 7 or less * A minimum of 12 biopsy cores sampled during diagnostic biopsy * Three or fewer biopsy cores with prostate cancer * No single biopsy core with greater than 50% of tumor involvement * A radiographically visible prostate lesion on MRI with concordance to biopsy sextant * A documented Karnofsky performance status of at least 70 * Estimated survival of 20 years or greater, as determined by treating physician * Ability to give informed consent Exclusion Criteria: * Previous surgery, radiation, or androgen deprivation therapy for prostate cancer * Presence of any condition (e.g., metal implant, shrapnel) not compatible with MRI * History of previous pelvic radiation * Severe lower urinary tract symptoms as measured by an International Prostate Symptom Score (IPSS) of 20 or greater. (See Appendix A) * History of other primary non-skin malignancy within previous three years