Multiple-Dose Study Apixaban in Pediatric Subjects With an Indwelling Central Venous Catheter

Inclusion Criteria: * Subjects with chronic stable disease with any type of functioning CVC in the upper or lower venous system (e.g., jugular, subclavian; femoral vein) that is anticipated to remain in the subject for the treatment portion of the study. * \> 12 to \<18 years of age Exclusion Criteria: * Current or recent (within 3 months of study drug administration) gastrointestinal disease or gastrointestinal surgery that, in the opinion of the investigator and the BMS Medical Monitor, could impact the absorption of the study drug * Active bleeding or high risk of bleeding