Immune Dysregulation in Hepatitis C Patients With or Without Arthritis

N/AUnknownNCT01195987

The Center for Rheumatic Disease, Allergy, & Immunology30 enrolled

Overview

The purpose of this study is to study the role of the Immune System in causing arthritis in patients with Hepatitis C.

Patients will provide one blood sample after qualifying for the study, and signing consent. The patients will have a skin test TB, Candida, and Trichophyton placed and will read the results themselves and mail back the card with the measurements to be recorded. Labs will test for ESR, CBC, CRP, antiCCP, Cryoglobulins, RF, CH50, C3, C4, Flow cytometry, and would have already been tested for HIV and Hepatitis C.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hepatitis C Patients

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All adults 18 or older, 20 will have hep C positive with a viral load withen 6 mo. of enrollment. * Either interferon or antiviral naive or those who failed interferon or antiviral therapy more than 6 mo. prior to enrollment. * 10 normal healthy controls- Hep C neg and without osteoarthritis (OA). Exclusion Criteria: * HIV patients * Those with concomitant alcoholic liver disease * Patients with Rheumatoid Arthritis (RA) or other autoimmune disorders.

Locations (1)

Center for Rheumatic Disease, Allergy & Immunology

Kansas City, Missouri, United States

RECRUITING

Central Contacts

Nabih I Abdou, MD, PhD

CONTACT

816-531-0930

Cindy A Greenwell, RN, BSN, CCRC

CONTACT

816-531-0930 cindy@centerforrheumatic.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.