A Study Evaluating the Efficacy of Administered Maintenance Treatments in Bipolar Disorder I and II.

Inclusion Criteria: * Subjects who experienced the last acute mood episode during the last 2 months and are in euthymic state (YMRS score ≤12 and HAM-D score ≤12) for at least two weeks * Diagnosis of bipolar disorder I or II (as per DSM-IV), with or without rapid cycling * Subjects who have been treated with at least one atypical antipsychotic for the management of an acute mood event (manic or depressive) as monotherapy or in combination with other medication * Provision of informed consent prior to study participation Exclusion Criteria: * Subjects fulfilling criteria for diagnosis of any other psychiatric condition (except from bipolar disorder I or II), as per DSM-IV Axis Ι, concomitant organic mental disorder or mental retardation * Subjects who have received treatment with a depot * Substance abuse or dependence (with the exception of nicotine dependence), as defined by DSM-IV criteria * Inability of subjects to comply with the study protocol.