The purpose of this study is to determine the effect of probiotic supplemented yogurt in reducing colonic transit time (CTT) in females between the ages of 18-65 years old. Two yogurts will be administered, one containing a specific strain of probiotic in the Bifidobacterium genus and the other without the probiotic supplement. It is hypothesized that subjects receiving the probiotic supplemented yogurt will experience reduced CTT and improved gastrointestinal comfort and quality of life compared to those receiving the non-probiotic supplemented yogurt.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
68
4 ounces (113g) of yogurt per day, for 14 days. Minimum Bifidobacterium dose of 1E+10 cfu/serving.
4 ounces (113g) of yogurt per day, for 14 days. No bifidobacterium added.
Georgetown University Department of Family Medicine, Research Division
Washington D.C., District of Columbia, United States
Colonic Transit Time
Time frame: 90 days
Frequency of bowel movements (daily)
Time frame: 90 days
Stool consistency (daily)
Time frame: 90 days
Well being as assessed by agreed upon quality of life instrument
Time frame: 90 days
Dietary intake survey
Time frame: 90 days
Tolerance
by questionnaire: e.g. bloating
Time frame: 90 days
Rome criteria
Time frame: 90 days
Bristol criteria
Time frame: 90 days
Recovery of the probiotic in the faeces (quantitative measure)
Time frame: 90 days
Bacterial composition of the fecal flora
Time frame: 90 days
Adverse events
Time frame: 90 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.