A COMparison Between PAClitaxel-coated Balloon and pacliTaxel-eluting Stent in the Treatment of In-Stent Restenosis (COMPACT-ISR)

Inclusion Criteria: * informed consent * \>18y * Stable Angina or Unstable Angina * Single restenotic lesion in a previously stented coronary artery Exclusion Criteria: * Acute Myocardial Infarction within 72h * Serum Creatinine\>2.0 mg/dL * Contraindications to ASA, Heparin, Clopidogrel, Ticlopidine, Abciximab, Tirofiban, Paclitaxel * Contraindications to contrast media * Life expectancy \< 2y * Target Lesion length \> 30mm * Target Lesion diameter \<= 2.5 mm * Target stenosis \< 70% * Massive Calcifications in the target segment * Evidence of intra-coronary thrombus