Telmisartan+Amlodipine Fixed Dose Combination in Hypertension

Inclusion criteria: 1. Aged at least 18 years at the date of signing the consent form 2. For treatment-naïve patients: hypertension defined by a mean seated diastolic blood pressure (DBP) equal or more than 100 mmHg measured by manual cuff sphygmomanometry at visit 1 and 2; For pretreatment patients: hypertension defined by a mean seated diastolic blood pressure equal or more than 90 mmHg at visit 1 and equal or more than 100 mmHg at visit 2 measured by manual cuff sphygmomanometry 3. 24-hour mean diastolic blood pressure equal or more than 85 mmHg at baseline Ambulatory Blood Pressure Monitoring Exclusion criteria: 1. mean seated systolic blood pressure equal or more than 200 mmHg and/or mean seated diastolic blood pressure equal or more than 120 mmHg 2. any clinically significant hepatic impairment 3. severe renal impairment 4. bilateral renal artery stenosis or renal artery stenosis in a solitary kidney or post-renal transplant 5. current treatment with any antihypertensive agents, whether or not prescribed for this indication, that cannot be safely stopped 6. other conditions or situations that could put potential participants at unacceptable risk due to participation in this study