The goal of this study is to compare supportive-expressive therapy, a type of psychodynamic psychotherapy, with cognitive therapy for the treatment of depression in community mental health consumers. Hypothesized mediators of treatment will also be examined.
The goal of this study is to conduct a randomized, comparative, non-inferiority clinical trial that tests the hypothesis that a widely used form of manualized dynamic psychotherapy (supportive-expressive psychodynamic therapy) is not inferior to cognitive therapy when implemented in community mental health settings for the treatment of major depressive disorder (MDD). The specific aims are (1) to conduct a randomized non-inferiority trial to compare supportive-expressive psychodynamic therapy and cognitive therapy for patients with MDD and (2) to assess the comparative effectiveness of supportive-expressive psychodynamic therapy and cognitive therapy on secondary measures of symptoms, patient functioning, and quality of life. Patient mediators of outcome will also be examined through an additional grant awarded to Paul Crits-Christoph, Ph.D. This grant was funded by the National Institutes of Mental Health - RO1MH092363-01. This grant is entitled:"The mechanisms of cognitive and dynamic therapy in community settings." Recruitment will occur solely through community mental health clinics in and around Philadelphia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
237
16 sessions of cognitive therapy administered weekly by a community mental health therapist
16 sessions of supportive-expressive psychodynamic therapy administered weekly by a community mental health therapist
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Hamilton Rating Scale for Depression (HAM-D)
Time frame: 6 months
BASIS-24
Time frame: 6 months
Beck Depression Inventory - II (BDI-II)
Time frame: 6 months
Medical Outcomes Study 36-Item Short Form (SF-36)
Measure of general functionality
Time frame: 6 months
Quality of Life Inventory (QOLI)
Time frame: 6 months
Ways of Responding (WOR)
Time frame: 2 months
Dysfunctional Attitudes Scale (DAS)
Time frame: 2 months
Psychological Distance Scaling Task (PDST)
Time frame: 2 months
Self-Understanding of Interpersonal Patterns Scale-Revised (SUIP-R)
Time frame: 2 months
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