In this randomized study The investigators aim to compare the growth of very-low-birth-weight (VLBW) infants fed either a high protein or a standard protein preterm infant formula. Babies will be fed the assigned formula between the time they achieve full enteral feeds and hospital discharge, for a minimum of 3 weeks. The weight gain (g/d) will be measured and compared between groups. Feeding tolerance, protein-energy status and body composition between the study groups will also be analysed. After discharge, babies will be fed a post-discharge preterm infant formula (PDF) between hospital discharge and 3 m corrected age.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
70
minimum 3 weeks feeding until hospital discharge
minimum 3 weeks feeding until hospital discharge
Department of Pediatrics St Louis University
St Louis, Missouri, United States
Service Universitaire de Néonatologie CHR de la Citadelle
Liège, Belgium
Service de néonatologie Hôpital de la Croix Rousse
Lyon, France
Department of Child Health Royal Victoria Infirmary
Newcastle upon Tyne, United Kingdom
comparison of weight gain between both study groups as a measure of safety
Time frame: 3 weeks
comparison of feeding tolerance and metabolic status between study groups as a measure of safety
Time frame: 3 weeks
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