Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives

Institut Curie350 enrolled

Overview

RATIONALE: Studying samples of blood in the laboratory from patients with cancer and their relatives may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at blood samples collected from patients with Ewing sarcoma and their relatives.

OBJECTIVES: * To identify and characterize a genetic susceptibility factor to Ewing's sarcoma by performing a Genome-Wide Association Study with as many as possible Ewing sarcoma patients. OUTLINE: This is a multicenter study. Blood samples are collected from patients and their relatives. Blood DNA samples are analyzed for susceptibility genes of Ewing Sarcoma.

Study Type

OBSERVATIONAL

Enrollment

350

Conditions

Sarcoma

Interventions

genome-wide association studyOTHER

Eligibility

Sex: ALLMin age: 0 YearsMax age: 120 YearsHealthy volunteers:

Medical Language ↔ Plain English

DISEASE CHARACTERISTICS: * Patients with Ewing sarcoma * Relatives of Ewing sarcoma patients PATIENT CHARACTERISTICS: * Patients with a fusion genes specific of Ewing Sarcoma PRIOR CONCURRENT THERAPY: * Not applicable

Locations (1)

Institut Curie Hopital

Paris, France

Outcomes

Primary Outcomes

Identification and characterization of susceptibility genes in patients with Ewing sarcoma

Time frame: Through study completion, an average of 10 years

Data from ClinicalTrials.gov

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